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Comment on:
Continuous popliteal sciatic nerve block. How to be sure the catheter works?
Ekatodramis G, Nadig M, Blumenthal S, Borgeat A.
Publication Types:
PMID: 15504200 [PubMed - indexed for MEDLINE]
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Effect of ephedrine on the onset time of succinylcholine.
Ganidagli S, Cengiz M, Baysal Z.
Department of Anaesthesiology and Reanimation, Harran University Medical School, Sanliurfa, Turkey. sganidagli@hotmail.com
BACKGROUND: The aim of this study was to evaluate the effect of ephedrine administered prior to induction of anaesthesia on the onset time of succinylcholine for endotracheal intubation. METHODS: Patients were randomly assigned to receive intravenously (i.v.) either 70 microg kg(-1) of ephedrine (Group I; n = 25) or saline (Group II; n = 25) 3 min before induction of anaesthesia. Induction of anaesthesia was provided with propofol 2 mg kg(-1) plus remifentanil 1 microg kg(-1). Onset time and duration of muscle fasciculation and onset time of succinylcholine were recorded. Intubation was attempted after establishment of 100% thumb relaxation and difficulties were recorded. Heart rate, pulse oxymetry (SpO2) and mean arterial pressure (MAP) were also recorded. RESULTS: The onset time of succinylcholine were significantly (P < 0.001) shorter in Group I (26 +/- 4 s), when compared with Group II (43 +/- 6 s). Patients in Group I were intubated at 49 +/- 7 s compared with 68 +/- 10 s in Group II. The score of intubation was similar in both groups. Duration of muscle fasciculation was longer in Group II. Heart rate and MAP increased significantly (P < 0.05) after ephedrine injection, compared with the baseline value in Group I. CONCLUSIONS: The onset time of succinylcholine can be shortened with ephedrine pretreatment.
Publication Types:
- Clinical Trial
- Randomized Controlled Trial
PMID: 15504193 [PubMed - indexed for MEDLINE]
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Clonidine vs. midazolam as premedication in children undergoing adeno-tonsillectomy: a prospective, randomized, controlled clinical trial.
Bergendahl HT, Lonnqvist PA, Eksborg S, Ruthstrom E, Nordenberg L, Zetterqvist H, Oddby E.
Department of Paediatric Anaesthesia and Intensive Care, Astrid Lindgrens Children's Hospital, Stockholm, Sweden. henrik.bergendahl@hs.se
BACKGROUND: Clonidine administration in the setting of paediatric anaesthesia is associated with a number of desirable effects, e.g. preoperative sedation, analgesia and reduced anaesthetic requirements. The aim of the current study was to compare postoperative outcome variables using a prospective, randomized, double-blind design after premedication with clonidine or midazolam. METHODS: One hundred paediatric ASA physical status 1 patients (age 1-11 year) scheduled for adeno-tonsillectomy were assigned to receive rectal premedication with midazolam (300 microg kg(-1) and atropine 40 microg kg(-1); group M, n = 52) or clonidine (5 microg kg(-1 and) atropine 40 microg kg(-1); group C, n = 48) prior to a standardized sevoflurane anaesthetic. The incidence of immediate postoperative pain (0-2 h), as assessed by repeated Objective Pain Scale (OPS) scores, was chosen as the primary end-point of the study. Degree of sedation (modified Vancouver sedation scale 0-3), occurrence of postoperative vomiting (POV), and incidence of shivering and immediate postoperative confusion were registered as secondary end-points. After hospital discharge parents were instructed to continue the evaluation of pain, sedation, POV and sleep pattern during a 24-h period. Parents were also asked for their preference concerning the postoperative behaviour of their child (calm, sedated vs. alert, active). RESULTS: In the early postoperative period patients in the clonidine group had a significantly lower sum of 5 OPS scores (median = 8.0) compared to group M (median = 11.5) (P = 0.011). Administration of clonidine was also associated with a slightly higher sum of sedation scores (median = 13) in the early postoperative period compared to children receiving midazolam (median = 12) (P < 0.001). No episode of shivering was observed in the clonidine group but was present in five of the patients in the midazolam group (P = 0.057). In younger children (< 5 years) the incidence of postoperative confusion was lower in the clonidine group (P = 0.001). No difference in the frequencies of POV incidences, degree of postoperative pain, need for analgesics, or sleep pattern during the first 24 postoperative hours could be observed between the groups according to the parental evaluation. Children premedicated with clonidine were more calm and sedated compared to children in the midazolam group (P = 0.024) as judged by their parents. A significant majority of parents (75%; P < 0.001) preferred a calm and sedated child during the first postoperative 24-h period. CONCLUSION: Rectal premedication with clonidine was associated with a significant reduction of pain in the early postoperative period compared to midazolam and was also associated with moderately increased sedation during the first 24 postoperative hours. The sedative effect of clonidine is in agreement with the unambiguous finding of a parental preference for a calm and sedated child during the first 24 postoperative hours.
Publication Types:
- Clinical Trial
- Randomized Controlled Trial
PMID: 15504191 [PubMed - indexed for MEDLINE]
-
Dixyrazine for the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy.
Glaser C, Sitzwohl C, Wallner T, Lerche A, Marhofer P, Schindler I.
Division of Anesthesiology and Intensive Care, Vienna City Hospital, Floridsdorf, Austria.
BACKGROUND: The study assessed the efficacy and safety of dixyrazine, an alternative neuroleptic drug to droperidol, in the prophylaxis of postoperative nausea and vomiting (PONV). METHODS: A total of 197 patients scheduled for laparoscopic cholecystectomy under general anesthesia were randomized to receive either dixyrazine 10 mg or placebo double-blinded at the end of surgery. Scores pertaining to PONV episodes, analgetic supply, rescue medication, adverse events and patient satisfaction were collected over the first 2 h in the PACU and the next 22 h in the ward. RESULTS: The incidence of PONV over the entire 24-h period was reduced from 32% in the placebo group to 13% in the dixyrazine group (P< or =0.004). The incidence of nausea in the first 2 h was reduced from 15% in the placebo group to 4% in the dixyrazine group (P< or =0.02) and from 12% to 5% in the next 22 h. The incidence of emetic episodes was not different between the two groups. Postoperative shivering was significantly less prevalent in the dixyrazine than in the placebo group (2% vs. 13%; P< or =0008), and opioid analgesics were required significantly less often (61% vs. 75%; P< or =0.01). No significant adverse effects were observed. Patient satisfaction was similar in both groups. CONCLUSION: Prophylactic dixyrazine is an effective, safe, and cheap antiemetic drug for laparoscopic cholecystectomy without involving any significant adverse events.
Publication Types:
- Clinical Trial
- Randomized Controlled Trial
PMID: 15504190 [PubMed - indexed for MEDLINE]
-
Comparison of the analgesic efficacy of ketobemidone and morphine for management of postoperative pain in children: a randomized, controlled study.
Jylli L, Lundeberg S, Langius-Eklof A, Olsson GL.
Pediatric Anesthesia and Intensive Care, Pain Treatment Service, Astrid Lindgren Children's Hospital, Karolinska Hospital, Department of Surgical Science, Karolinska Institutet, Stockholm, Sweden. leena.jylli@kirurgi.ki.se
BACKGROUND: Ketobemidone has been used as an analgesic for postoperative pain in children, but to our knowledge the effect and occurrence of adverse effects of ketobemidone compared to morphine is not known. The aim was to determine if the analgesic potency and the occurrence of adverse effects of ketobemidone differ from morphine when administered to children, as measured by patient-controlled analgesia consumption (PCA) for postoperative pain. METHODS: Sixty healthy children, aged 6 to 16 years, scheduled for elective surgery were randomized to receive either ketobemidone (Ke) 1 mg ml(-1) or morphine (Mo) 1 mg ml(-1) for postoperative pain through PCA. Drug consumption (microg kg(-1) h(-1)), the number of PCA doses, pain intensity, and adverse effects were recorded at regular intervals. RESULTS: Data on total drug consumption were based on 26 children in the Ke group and 28 in the Mo group. A non-statistically significant difference for total mean consumption of ketobemidone (18.6 microg kg(-1)h(-1)) and morphine (23.2 microg kg(-1)h(-1)) was obtained. The mean dose ratio (Mo/Ke) was 0.80 and the median was 0.94. Children's characteristics, loading dose, PCA doses, VAS scores, and adverse effects showed no significant differences between the groups. CONCLUSION: The analgesic potency and adverse effects of ketobemidone are similar to morphine when used for postoperative pain management in children.
Publication Types:
- Clinical Trial
- Randomized Controlled Trial
PMID: 15504185 [PubMed - indexed for MEDLINE]
-
Intrathecal adenosine increases spinal cord blood flow in the rat: measurements with the laser-Doppler flowmetry technique.
Rane K, Segerdahl M, Karlsten R.
Department of Anaesthesia and Intensive Care, Danderyd Hospital, Sweden. ulf.kerstin@chello.se
BACKGROUND: Adenosine and adenosine analogues induce antinociception both after systemic and intrathecal (i.t.) administration in animal models. Further, patients with neuropathic pain have been treated successfully with i.t. adenosine. Prior to introducing new analgesic drugs for regular spinal use in humans, experimental studies must be undertaken to evaluate the risks of neurotoxicity. It is important to evaluate the possibility of cytotoxic effects and that antinociception may be due to decreased spinal cord blood flow (SCBF) and neural ischaemia. The present study evaluates whether adenosine or isotonic mannitol induces changes in SCBF as assessed by laser-Doppler flowmetry (LDF). METHODS: After laminectomy and insertion of i.t. catheters, seven rats received adenosine 50 microg in isotonic mannitol 500 microg, six rats received isotonic mannitol 500 microg and eight rats received saline 0.9%. SCBF was registered by the LDF technique continuously for 3 h after injection. Arterial blood pressure was also assessed. RESULTS: In the adenosine in mannitol group, SCBF increased up to 230% of baseline levels for almost 40 min, P = 0.044 and then declined. In the mannitol group, SCBF increased up to 180% of baseline (P < 0.011) before declining. At 60 min, SCBF had returned to saline levels and remained stable during the rest of the experiment. CONCLUSION: Intrathecal administration of adenosine in mannitol and of mannitol both increased SCBF in rats, compared with saline. It is unlikely that the effects on SCBF induced by adenosine and mannitol could result in neurotoxicity of the spinal cord.
PMID: 15504184 [PubMed - indexed for MEDLINE]
Comment on:
Adequate preoperative fasting and aspiration: factors affecting regurgitation.
Salem MR, Gaucher D, Joseph NJ.
Publication Types:
- Case Reports
- Comment
- Letter
PMID: 15618814 [PubMed - indexed for MEDLINE]
-
Ketamine for perioperative pain management.
Himmelseher S, Durieux ME.
Department of Anesthesiology, University of Virginia Health System, Charlottesville, Virginia 22908-0710, USA.
Publication Types:
PMID: 15618805 [PubMed - indexed for MEDLINE]
-
Double epidural catheter with ropivacaine versus intravenous morphine: a comparison for postoperative analgesia after scoliosis correction surgery.
Blumenthal S, Min K, Nadig M, Borgeat A.
Department of Anesthesiology, Orthopedic University Hospital Balgrist, Zurich, Switzerland.
BACKGROUND: Major spine surgery with a dorsal or ventrodorsal approach causes severe postoperative pain. The use of continuous epidural analgesia through one or two epidural catheters placed intraoperatively by the surgeon has been shown to provide efficient postoperative pain control. In this prospective unblinded study, the authors compared the efficacy of continuous intravenous morphine with a continuous double epidural catheter technique with ropivacaine after scoliosis correction. METHODS: Thirty patients with American Society of Anesthesiology physical status I-III were prospectively randomized to either the morphine group or the epidural group. At the end of surgery, patients in the epidural group received two epidural catheters placed by the surgeon, one directed cephalad and one caudally. Correct placement was checked radiographically. Postoperative analgesia until the first postoperative morning was performed with remifentanil target-control infusion for all patients. From that time remifentanil was stopped and continuous intravenous analgesia with morphine or double epidural analgesia with ropivacaine 0.3% was initiated (T0 = beginning of study). Pain at rest and pain in motion (using a visual analog scale from 0-100), the amount of rescue analgesics, sensory level, motor blockade, postoperative nausea and vomiting, and pruritus were assessed every 6 h and bowel function was assessed every 12 h until T72 (end of study). Two days later, patient satisfaction was assessed. RESULTS: Pain scores at rest were significantly decreased in the epidural group at all time points except at T12, T60, and T72. Pain scores in motion were significantly decreased in the epidural group at T24, T48, and T72. Bowel activity was significantly better in the epidural group at T24, T36, T48, and T60. Postoperative nausea and vomiting and pruritus occurred significantly less frequently in the epidural group. No complications related to the epidural catheter occurred. CONCLUSIONS: Both methods provide efficient postoperative analgesia. However, double epidural catheter technique provides better postoperative analgesia, earlier recovery of bowel function, fewer side effects, and a higher patient satisfaction.
Publication Types:
- Clinical Trial
- Randomized Controlled Trial
PMID: 15618801 [PubMed - indexed for MEDLINE]
-
Single acceleromyographic train-of-four, 100-Hertz tetanus or double-burst stimulation: which test performs better to detect residual paralysis?
Samet A, Capron F, Alla F, Meistelman C, Fuchs-Buder T.
Department of Anesthesia and Critical Care, CHU Nancy/Brabois, Nancy, France.
BACKGROUND: Acceleromyography is regularly used as an isolated test to detect residual paralysis. The performance of acceleromyography, however, has not been investigated for the setting where calibration is impossible. This study first evaluated the reliability of a single acceleromyographic train-of-four (TOF) ratio (T4/T1) to detect residual paralysis and compared it with tactile estimation of fade after double-burst stimulation and 100-Hz, 5-s tetanus. The second part of the study investigated whether uncalibrated acceleromyographic TOF ratio can predict time to complete recovery. METHODS: Anesthesia was induced and maintained with propofol and sufentanil. In the first part of the study (n = 40) neuromuscular blockade was assessed by mechanomyography. After signal stabilization 0.15 mg/kg cisatracurium was given. At the end of surgery a first physician evaluated manual fade after double-burst stimulation, then, in the same patient, a single acceleromyographic TOF ratio was recorded; thereafter a second physician, unaware of the results, assessed fade after a 100-Hz, 5-s tetanus. Sensitivity, specificity, and negative and positive predictive value of the three tests to detect a mechanomyographic TOF > or =0.9 were calculated. In the second part of the study (n = 25) neuromuscular recovery was assessed simultaneously with mechanomyography and uncalibrated acceleromyography (current set manually at 60 mA); the time intervals from acceleromyographic TOF ratios of 0.6, 0.7, 0.8, and 0.9 until complete recovery, i.e., adductor pollicis mechanomyography 0.9 TOF ratios, were determined. RESULTS: The sensitivity of double burst stimulation was 29% (95% confidence interval [CI], 13-45%), its specificity was 100%, the negative predictive value was 29% (95% CI, 13-45%), and the positive predictive value was 100%. For a single acceleromyographic TOF ratio the respective values were 70% (95% CI, 54-86%), 88% (95% CI, 67-100%), 47% (95% CI, 23-71%) and 95% (95% CI, 86-100%). The respective values for 100-Hz, 5-s tetanus were 74% (95% CI, 59-89%), 55% (95% CI, 23-88%), 38% (95% CI, 12-64%), and 85% (95% CI, 72 -99%). At an uncalibrated acceleromyographic TOF ratio was 0.6, complete recovery occurred within 16 min (95% CI, 13.5-17.8 min). At acceleromyographic TOF ratios of 0.7, 0.8, and 0.9 this time interval was 12.5 min (95% CI, 10.2-14.8 min), 8 min (95% CI, 6.1-9.9 min), and 4 min (95% CI, 2.7-5.8 min), respectively. CONCLUSIONS: Acceleromyographic TOF performed better than double-burst stimulation or 100 Hz tetanus, but it did not reliably detect low degrees of residual paralysis when used as an isolated test at the end of surgery. The uncalibrated acceleromyographic TOF ratio, however, did predict the time to complete recovery.
PMID: 15618786 [PubMed - indexed for MEDLINE]
 
Delayed hypersensitivity due to epidural block with ropivacaine.
Ban M, Hattori M.
Hashima City Hospital, 3-246 Shinseicho, Hashima City 501-6206, Japan. masanoriban@k5.dion.ne.jp
Publication Types:
PMID: 15677657 [PubMed - indexed for MEDLINE]
Recent advances in intravenous anaesthesia.
Parris-Piper T, Sneyd JR.
Auckland, New Zealand.
PMID: 15703308 [PubMed - in process]
-
Dural ectasia: a likely cause of inadequate spinal anaesthesia in two parturients with Marfan's syndrome.
Lacassie HJ, Millar S, Leithe LG, Muir HA, Montana R, Poblete A, Habib AS.
Department of Anaesthesiology, Pontificia Universidad Catolica de Chile, Marcoleta 367, Santiago 833-0024, Chile; Department of Anaesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
We report two cases of Caesarean section in patients with Marfan's syndrome where continuous subarachnoid anaesthesia failed to provide an adequate surgical block. This was possibly because of dural ectasia, which was confirmed by a computed tomography scan in both cases.
PMID: 15695549 [PubMed - as supplied by publisher]
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Combined ilioinguinal blockade and local infiltration anaesthesia for groin hernia repair--a double-blind randomized study.
Andersen FH, Nielsen K, Kehlet H.
Surgical Clinic Charlottenlund, Copenhagen, Denmark.
BACKGROUND: Local infiltration anaesthesia for inguinal hernia repair is cost-effective, but fear of intra-operative pain may hinder its widespread use. It is unknown whether a combined ilioinguinal blockade and local infiltration anaesthesia improves intra-operative analgesia. METHODS: We performed a double-blind randomized study in 160 patients undergoing inguinal hernia mesh repair under local infiltration anaesthesia with or without additional ilioinguinal blockade. Intra-operative pain and pain at 24 and 48 h postoperatively and analgesic requirements (acetaminophen, ibuprofen, and tramadol) were assessed. RESULTS: Median intra-operative pain scores were reduced (P=0.02) from 13 to 9 with additional ilioinguinal blockade, with no differences in requirement for sedation. There were significantly (P<0.05) more patients with intra-operative visual analogue pain scale >/=30 in the placebo group vs the ilioinguinal blockade group. Postoperative pain scores and analgesic requirements were similar. CONCLUSION: Combined ilioinguinal blockade and local infiltration anaesthesia is recommended for groin hernia repair to reduce intra-operative pain.
PMID: 15695545 [PubMed - as supplied by publisher]
Continuous positive airway pressure for treatment of postoperative hypoxemia: a randomized controlled trial.
Squadrone V, Coha M, Cerutti E, Schellino MM, Biolino P, Occella P, Belloni G, Vilianis G, Fiore G, Cavallo F, Ranieri VM; Piedmont Intensive Care Units Network (PICUN).
Dipartimento di Anestesia, Azienda Ospedaliera S.Giovanni Battista-Molinette, Universita di Torino, Italy.
CONTEXT: Hypoxemia complicates the recovery of 30% to 50% of patients after abdominal surgery; endotracheal intubation and mechanical ventilation may be required in 8% to 10% of cases, increasing morbidity and mortality and prolonging intensive care unit and hospital stay. OBJECTIVE: To determine the effectiveness of continuous positive airway pressure compared with standard treatment in preventing the need for intubation and mechanical ventilation in patients who develop acute hypoxemia after elective major abdominal surgery. DESIGN AND SETTING: Randomized, controlled, unblinded study with concealed allocation conducted between June 2002 and November 2003 at 15 intensive care units of the Piedmont Intensive Care Units Network in Italy. PATIENTS: Consecutive patients who developed severe hypoxemia after major elective abdominal surgery. The trial was stopped for efficacy after 209 patients had been enrolled. INTERVENTIONS: Patients were randomly assigned to receive oxygen (n = 104) or oxygen plus continuous positive airway pressure (n = 105). MAIN OUTCOME MEASURES: The primary end point was incidence of endotracheal intubation; secondary end points were intensive care unit and hospital lengths of stay, incidence of pneumonia, infection and sepsis, and hospital mortality. RESULTS: Patients who received oxygen plus continuous positive airway pressure had a lower intubation rate (1% vs 10%; P = .005; relative risk [RR], 0.099; 95% confidence interval [CI], 0.01-0.76) and had a lower occurrence rate of pneumonia (2% vs 10%, RR, 0.19; 95% CI, 0.04-0.88; P = .02), infection (3% vs 10%, RR, 0.27; 95% CI, 0.07-0.94; P = .03), and sepsis (2% vs 9%; RR, 0.22; 95% CI, 0.04-0.99; P = .03) than did patients treated with oxygen alone. Patients who received oxygen plus continuous positive airway pressure also spent fewer mean (SD) days in the intensive care unit (1.4 [1.6] vs 2.6 [4.2], P = .09) than patients treated with oxygen alone. The treatments did not affect the mean (SD) days that patients spent in the hospital (15 [13] vs 17 [15], respectively; P = .10). None of those treated with oxygen plus continuous positive airway pressure died in the hospital while 3 deaths occurred among those treated with oxygen alone (P = .12). CONCLUSION: Continuous positive airway pressure may decrease the incidence of endotracheal intubation and other severe complications in patients who develop hypoxemia after elective major abdominal surgery.
Publication Types:
- Clinical Trial
- Multicenter Study
- Randomized Controlled Trial
PMID: 15687314 [PubMed - indexed for MEDLINE]
-
Clinical guideline on behavior management.
American Academy of Pediatric Dentistry.
Publication Types:
- Guideline
- Practice Guideline
PMID: 15656443 [PubMed - indexed for MEDLINE]
-
Oral health policies.
American Academy of Pediatric Dentistry.
Publication Types:
PMID: 15656435 [PubMed - indexed for MEDLINE]
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Comparison of oral midazolam with and without hydroxyzine in the sedation of pediatric dental patients.
Shapira J, Kupietzky A, Kadari A, Fuks AB, Holan G.
Department of Pediatric Dentistry, Hebrew University-Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
PURPOSE: The purpose of this study was to compare the effectiveness of midazolam (MDZ) alone to a combination of MDZ and hydroxyzine (MDZH) when sedating young children for dental treatment. METHODS: This was a prospective, double-blinded, crossover clinical study of young uncooperative children in need of at least 2 restorative visits. Twenty-eight children, ages 21 to 56 months, with a mean age of 36.6 months, participated in this study. The subjects were assigned randomly to receive either 0.5 mg/kg of oral MDZ 20 minutes prior to the beginning of dental treatment or the combination of 0.3 mg/kg oral MDZ with 3.7 mg/kg of hydroxyzine 30 minutes before treatment. The alternative drug regimen was administered at the second appointment. All subjects also received 50% nitrous oxide and were restrained with a papoose board. The child's behavior (quiet or crying, relaxed or moving) was evaluated every 5 minutes by an experienced pediatric dentist who was unaware of the drug given to the child. At the conclusion of treatment, each session was evaluated for overall effectiveness. RESULTS: Regardless of the type of premedication, more patients exhibited quiet behavior at the beginning of treatment, with an increase in crying and movement toward the end of treatment. Regarding movement, a significant difference was observed during the first 20 minutes between the 2 regimens. MDZ showed more children exhibiting movement. During the first 30 minutes of treatment, more children cried in the MDZ group, while MDZH presented more children asleep or quiet. No significant differences were found in behavior as a function of the order the sedative regimens were given. No significant differences between the 2 regimens regarding overall behavior and success (t=0.655 at 27 degrees of freedom; P=.518) were found. CONCLUSIONS: The combination of hydroxyzine (3.7 mg/kg) with MDZ (0.3 mg/kg) administered 30 minutes before treatment resulted in safe and effective sedation for the dental treatment of young children. This combination's use might be more advantageous when compared to MDZ alone, resulting in less crying and movement during the first 30 and 20 minutes, respectively.
Publication Types:
- Clinical Trial
- Randomized Controlled Trial
PMID: 15646910 [PubMed - indexed for MEDLINE]
-
The wand versus traditional injection for mandibular nerve block in children and adolescents: perceived pain and time of onset.
Palm AM, Kirkegaard U, Poulsen S.
Municipal Dental Service for Children and Adolescents, Frederikssund, Denmark.
PURPOSE: The purpose of this study was to compare the perception of pain and time of onset in relation to mandibular alveolar nerve block administered by a computerized anesthesia delivery system (ie, The Wand) and a traditional anesthesia system (ie, the syringe). METHODS: This study was conducted according to a split-mouth design, with both types of injections being given to all patients. Subjects consisted of 33 patients between 7 and 18 years of age requiring local anesthesia for dental restorations in both sides of the mandible. All patients were blindfolded, and the sound from the Wand machine was activated during both types of administration. Topical analgesic was placed in the area of the injection site in all cases. Pain ratings were obtained using a 10-point visual analog scale (VAS). Time of onset was measured, from withdrawal of the needle to numbness of the lower lip was reported. RESULTS: The computerized anesthesia delivery system resulted in significantly lower pain ratings than the traditional syringe. No difference could be found in time of onset between the 2 methods. CONCLUSIONS: Mandibular alveolar block analgesia seems to be less painful when using The Wand than when using a traditional syringe.
Publication Types:
- Clinical Trial
- Randomized Controlled Trial
PMID: 15646908 [PubMed - indexed for MEDLINE]
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