Ann Emerg Med 2001 Sep;38(3):347-8

The use of physostigmine in the management of gamma-hydroxybutyrate overdose.

Mullins ME, Dribben W

[Medline record in process]

Publication Types:

PMID: 11547795, UI: 21429762

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Ann Intern Med 2001 Aug 21;135(4):239-47

Escherichia coli O157 and Salmonella infections associated with sprouts in California, 1996-1998.

Mohle-Boetani JC, Farrar JA, Werner SB, Minassian D, Bryant R, Abbott S, Slutsker L, Vugia DJ

Disease Investigations and Surveillance Branch, Division of Communicable Diseases Control, 2151 Berkeley Way, Room 708, Berkeley, CA 94704, USA. jmohlebo@dhs.ca.gov

BACKGROUND: In California, from 1996 through 1998, more than 50% of multicounty outbreaks with confirmed food vehicles were related to alfalfa or clover sprouts. OBJECTIVE: To summarize investigations of sprout-associated outbreaks. DESIGN: Matched case-control studies. SETTING: California. PATIENTS: Outbreak-associated patients and matched population controls. MEASUREMENTS: Matched odds ratios and 95% CIs; traceback and environmental investigations of sprout and seed growers; and pulsed-field gel electrophoresis of isolates from patients, sprouts, and seeds. RESULTS: Five sprout-associated outbreaks of salmonellosis and one outbreak of infection with nonmotile Shiga toxin-producing Escherichia coli O157 occurred. Six hundred patients had culture-confirmed disease, and two died. It is estimated that these outbreaks caused 22 800 cases of gastrointestinal illness or urinary tract infection. In the case-control studies, odds ratios for the association between illness and alfalfa sprout consumption ranged from 5.0 to infinity (all were statistically significant). Three sprout growers were implicated, and each was associated with two outbreaks. Outbreak strains of Salmonella were isolated from sprouts supplied by two sprout growers and from seeds used by the third sprout grower. CONCLUSIONS: As currently produced, sprouts can be a hazardous food. Seeds can be contaminated before sprouting, and no method can eliminate all pathogens from seeds. Seed and sprout growers should implement measures to decrease contamination. The general public should recognize the risks of eating sprouts, and populations at high risk for complications from salmonellosis or E. coli O157 infection should avoid sprout consumption.

PMID: 11511138, UI: 21402286

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Br J Dermatol 2001 Jul;145(1):185

Cutaneous malignancy in arsenicosis.

Saha KC

Publication Types:

PMID: 11453941, UI: 21347137

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Forensic Sci Int 2001 Aug 15;120(1-2):127-31

Morphine extraction in necrophagous insects remains for determining ante-mortem opiate intoxication.

Bourel B, Tournel G, Hedouin V, Deveaux M, Goff ML, Gosset D

Laboratoire Environnement et Sante, Faculte Libre des Sciences et Faculte Libre de Medecine, Institut Catholique de Lille, 56 rue du port, 59046 Lille Cedex, France.

To study the potential use of insects remains as toxicological indicators, we measured morphine in desiccated entomological materials using a radioimmunoassay method (Coat-A-Count Serum Morphine, Dade Behring, France) following enzymatic hydrolysis.First, enzymatic cuticle extraction of morphine (pronase digestion preceded by a 2h incubation with a dithiothreitol solution) was performed on various substrates (Calliphoridae puparial cases and desiccated adults, and desiccated pupae of Dermestidae) which were then tested to identify possible interferences with the radioimmunoassay procedure.This same procedure was performed on puparial cases and desiccated adults of Lucilia sericata (Diptera, Calliphoridae) previously reared on minced meat containing various morphine concentrations. Morphine was detected only in cuticle powder from insects reared on meats containing 100 and 1000mg/kg. Higher concentrations were measured in puparial cases. Rearings on psoas from eight heroin overdose victims confirmed previous experimental results.Remains of necrophagous insects, particularly puparial cases, are often preserved for a long time, and consequently can serve as late alternative specimens for toxicological analysis when suitable tissues are not available.

PMID: 11457620, UI: 21349974

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Gastroenterol Clin Biol 2001 Apr;25(4 Suppl):B152-6

[Hepatitis C virus and human immunodeficiency virus co-infection].

Pol S

Hepatologie, Hopital Necker, 149, rue de Sevres, 75015 Paris.

Publication Types:

PMID: 11449156, UI: 21341891

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Gastroenterol Clin Biol 2001 Apr;25(4):430-2

[Severe acute hepatitis associated with ibuprofen treatment].

Borel I, Hedelius F, Baumgartner C, Vial T, Scoazec JY, Dumortier J

Publication Types:

PMID: 11449133, UI: 21341910

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J Clin Psychiatry 2001 Jul;62(7):570-1

Remission of SSRI-induced akathisia after switch to nefazodone.

Chelben J, Strous RD, Lustig M, Baruch Y

Publication Types:

PMID: 11488371, UI: 21380548

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N Engl J Med 2001 Aug 23;345(8):618-9

Cutaneous reactions to STI571.

Brouard M, Saurat JH

Publication Types:

PMID: 11529225, UI: 21394616

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