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Am J Emerg Med 2002 Nov;20(7):624-6

A randomized paired comparison trial of cutaneous treatments for acute jellyfish (Carybdea alata) stings.

Nomura JT, Sato RL, Ahern RM, Snow JL, Kuwaye TT, Yamamoto LG

Emergency Department, Kapiolani Medical Center For Women And Children, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA.

The objective of the study was to compare cutaneous treatments (heat, papain and vinegar) for acute jellyfish (Carybdea alata) stings. Healthy adult volunteer subjects received a single-tentacle jellyfish sting on each forearm. One forearm was treated with hot-water immersion (40-41 degrees C). This was compared with the other forearm, which was randomized to a comparison treatment of papain meat tenderizer or vinegar. Pain was measured at 0, 2, 4, 6, 8, 10, 15, and 20 minutes using a 10-cm visual analog scale (VAS). For 25 subject runs, the average VAS scores at t = 0 were 3.6 cm (hot water) and 3.7 cm (comparison treatment). At t = 4 minutes (2 minutes after treatment had started), the differences between hot-water and comparison group VAS scores were 2.1 cm versus 3.2 cm, respectively. The mean difference between hot-water and comparison treatments was 1.1 cm (95% confidence interval, 0.6 to 1.6). At t = 20 minutes (the end of the study period), the differences between hot-water and comparison group VAS scores were 0.2 cm versus 1.8 cm, respectively. The mean difference between hot-water and comparison treatments was 1.6 cm (95% confidence interval, 0.9 to 2.3). This study suggests that the most efficacious initial treatment for C alata jellyfish envenomation is hot-water immersion to the afflicted site. Copyright 2002, Elsevier Science (USA). All rights reserved.)

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PMID: 12442242, UI: 22328506

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BMJ 2002 Dec 7;325(7376):1332-3

Fatal toxicity of serotoninergic and other antidepressant drugs: analysis of United Kingdom mortality data.

Buckley NA, McManus PR

Department of Clinical Pharmacology and Toxicology, Canberra Hospital, PO Box 11, Woden, ACT 2606, Australia. nick.buckley@act.gov.au

PMID: 12468481, UI: 22355457

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JAMA 2002 Dec 4;288(21):2675-6

Listeriosis outbreak prompts action--finally.

Voelker R

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PMID: 12460071, UI: 22349995

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Med J Aust 2002 Oct 21;177(8):460

Death and paramethoxyamphetamine - an evolving problem.

Jacobs W

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PMID: 12381261, UI: 22269808

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Med J Aust 2002 Oct 21;177(8):440-3

Black cohosh and other herbal remedies associated with acute hepatitis.

Whiting PW, Clouston A, Kerlin P

Princess Alexandra Hospital, Woolloongabba, QLD, Australia.

Six patients presented with clinical, biochemical and histological evidence of severe hepatitis after taking herbal remedies. One patient required urgent liver transplantation for fulminant hepatic failure after the brief use of black cohosh. Five patients took a combination of herbs and presented with jaundice, fatigue and pruritus. Healthcare providers and members of the public should be aware of the potential adverse effects of these remedies.

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PMID: 12381254, UI: 22269801