5 citations found

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Ann Pharmacother 2002 Jun;36(6):1085-9

Fomepizole as an antidote for ethylene glycol poisoning.

Battistella M

Marisa Battistella BSc Phm, Internal Medicine Clinical Pharmacist, University Health Network - Pharmacy Department ENG 260, 200 Elizabeth St., Toronto, Ontario M5G 2C4, Canada, FAX 416/340-3685, marisa.battistella@uhn.on.ca

[Medline record in process]

OBJECTIVE: To assess the use of fomepizole in the treatment of ethylene glycol poisoning in the absence of hemodialysis. DATA SOURCES: A MEDLINE search (1966-May 2001) of English-language literature pertaining to the use of fomepizole in ethylene glycol poisoning was performed. Key search terms included fomepizole, ethylene glycol poisoning, and hemodialysis. References cited in those articles were also evaluated. DATA SYNTHESIS: Results from a number of case reports and a prospective trial suggest that fomepizole is a safe and effective antidote in the treatment of ethylene glycol poisoning. CONCLUSIONS: Case reports and 1 prospective trial have shown that, in the absence of both renal dysfunction and significant metabolic acidosis, the use of fomepizole should obviate the need for hemodialysis. However, the decision to add hemodialysis in the treatment of ethylene glycol poisoning based on plasma ethylene glycol concentrations is still debatable. A randomized, controlled trial is needed to determine the exact criteria for adding hemodialysis.

PMID: 12022913, UI: 22017628


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Lancet 2002 May 11;359(9318):1685

Metastasising porocarcinoma following exposure to poison gas.

Helmke B, Starz H, Bachter D, Balda BR

Department of Dermatology and Allergology, Klinikum Augsburg, Stenglinstrasse 2, D-86156, Augsburg, Germany

[Medline record in process]

PMID: 12020547, UI: 22016313


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Lancet 2002 Apr 27;359(9316):1527

The African challenge.

Lalloo DG, Theakston RD, Warrell DA

Publication Types:

PMID: 11988287, UI: 21984385


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Med J Aust 2002 Mar 4;176(5):242

Mirtazapine-induced akathisia.

Girishchandra BG, Johnson L, Cresp RM, Orr KG

Publication Types:

PMID: 11999246, UI: 21993889


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Med J Aust 2002 Mar 4;176(5):240-1

Serotonin toxicity with therapeutic doses of dexamphetamine and venlafaxine.

Prior FH, Isbister GK, Dawson AH, Whyte IM

Publication Types:

PMID: 11999244, UI: 21993887


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