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Ciprofloxacin-induced acute generalized exanthematous pustulosis mimicking bullous drug eruption confirmed by a positive patch test.
Hausermann P, Scherer K, Weber M, Bircher AJ.
Department of Dermatology, University Hospital Basel, Switzerland.
We report the case of an 80-year-old woman presenting with ciprofloxacin-induced acute generalized exanthematous pustulosis (AGEP) confirmed by a positive patch test. Cutaneous morphology, course and histological findings were consistent with a definite diagnosis according to the AGEP validation score of the EuroSCAR study group. We point to the rarity of quinolone-induced AGEP and discuss immunological mechanisms, the value of in vivo and in vitro tests as well as the main differential diagnosis. Furthermore, we highlight in this particular case the challenging differentiation from bullous drug eruption. Copyright 2005 S. Karger AG, Basel.
Publication Types:
PMID: 16205075 [PubMed - indexed for MEDLINE]
Pattern of stingray injuries reported to Texas poison centers from 1998 to 2004.
Forrester MB.
Texas Department of State Health Services, 1100 W 49th Street, Austin, TX 78756, USA. mathias.forrester@dshs.state.tx.us
This study examined the relationship between selected factors and all human exposures involving stingray injuries reported to Texas poison centers. Cases were obtained retrospectively from calls to poison centers in Texas and included all reported human exposures involving stingray injuries from 1998 to 2004. The distribution of cases was determined for a variety of demographic and clinical parameters. A total of 153 cases were identified. The reported stingray injury penetrance increased during the 7-year period. Of the cases with a known patient age, 2% were <6 years, 25% were 6-19 years and 73% were >19 years. The stingray injuries occurred in public areas in 54% of the cases. In 61% of cases, the management site was reported not to be a health care facility. Of the cases with a known clinical outcome, none involved no effects and 53% involved minor effects. The highest proportion of stingray injuries occurred during the summer months, particularly August. In 60% of the cases, the calls originated from counties along the coast. This information can be used to identify those portions of the population most in need of education regarding the prevention and treatment of stingray injuries.
PMID: 16408617 [PubMed - in process]
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A retrospective study of mushroom poisoning in Iran.
Pajoumand A, Shadnia S, Efricheh H, Mandegary A, Hassanian-Moghadam H, Abdollahi M.
Loghman-Hakim Hospital Poison Center, Faculty of Medicine, Shaheed-Beheshti University of Medical Sciences, Tehran, Iran.
The objective of this study was to describe the pattern of mushroom poisoning in adults admitted to the Loghman-Hakim Hospital Poison Center from 1992 to 2002. All patients > or = 12 years of age were included in the study. The frequency of mushroom poisoning with respect to age, sex, season, reason, place of residence, latent phase, clinical and laboratory findings, treatment, and outcome of patients was investigated. Of the 72421 poisoning cases admitted to Loghman-Hakim Hospital Poison Center from 1992 to 2002, only 37 were poisoned by consumption of toxic mushrooms. As some of the patients' files were incomplete, only 25 files were included in the study. Of this number, 68% were male. The patients' age ranged between 12 and 65 years, with a mean of 31 years of age. All cases were accidental and mostly from Tehran (36%) and the northern provinces (rainy woodlands) of Iran (32%). Autumn was the most common season for poisoning with a frequency of 80%. The latent phase of poisonings was between 0.5 and 12 hours. The most frequently reported symptoms were vomiting (84%), nausea (60%), abdominal pain (60%) and diarrhea (40%). Jaundice was observed in 44% of cases, with a 50% rate of hepatic encephalopathy. A total of 66% of patients were discharged and the duration range of hospitalization was 1-12 days. In conclusion, people should be more informed of the dangers posed by wild mushrooms. Training of physicians and nurses in the accurate diagnosis and management of patients poisoned with poisonous mushrooms would improve the rate of survival.
PMID: 16408613 [PubMed - in process]
Succimer therapy for congenital lead poisoning from maternal petrol sniffing.
Powell ST, Bolisetty S, Wheaton GR.
Paediatrics, Tamworth Base Hospital, PO Box 640, Tamworth, NSW, 2340. Suzanna.Powell@hnehealth.nsw.gov.au.
An infant, born at 35 weeks' gestation to a woman who sniffed petrol, had a cord blood lead level eight times the accepted limit. Treatment with oral dimercaptosuccinic acid promptly reduced his blood lead levels. To our knowledge, this is the first reported case of congenital lead poisoning secondary to maternal petrol sniffing. We suggest that at-risk pregnancies should be identified, cord blood lead levels tested, and chelation therapy and developmental follow-up offered to affected infants.
PMID: 16411875 [PubMed - in process]
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