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Neurology 2002 Nov 12;59(9):1450-3
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Sensitization of trigeminal nociception specific for migraine but not pain of sinusitis.
Katsarava Z, Lehnerdt G, Duda B, Ellrich J, Diener HC, Kaube H.
Department of Neurology, University of Essen, Germany. zaza.katsarava@uni-essen.de
Trigeminal pain processing was studied in 14 patients with unilateral migraine attacks and 14 age- and sex-matched patients with comparable unilateral headache from frontal sinusitis. Using a nociception-specific blink reflex method (nBR), a facilitation of nBR responses predominantly on the headache side was observed in migraine, but not in sinusitis. The facilitation of trigeminal nociception may be specific for migraine rather than a consequence of peripheral pain such as frontal sinusitis.
PMID: 12427905 [PubMed - in process]