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Continuous maxillary and mandibular nerve block for perioperative pain relief: the excision of a complicated pleomorphic adenoma.
Kumar A, Banerjee A.
Department of Anaesthesiology and Critical Care, UCMS and GTB Hospital, Delhi, India. prof_ashok@rediffmail.com
A 68-yr-old hypertensive patient with ischemic heart disease and intractable atrial fibrillation with stable hemodynamics and poor chest compliance underwent pleomorphic adenoma of the parotid gland using regional anesthesia with continuous propofol sedation. Continuous maxillary and mandibular nerve blocks were performed and excision was performed with complete intraoperative and postoperative pain relief without compromising the patient's hemodynamic variables.
Publication Types:
PMID: 16244026 [PubMed - in process]
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Validation of a behavioral pain scale in critically ill, sedated, and mechanically ventilated patients.
Aissaoui Y, Zeggwagh AA, Zekraoui A, Abidi K, Abouqal R.
Service de Reanimation Medicale et Toxicologie Clinique, BP 1005, Hopital Ibn Sina, 10001 Rabat, Morocco. shadowyounes@hotmail.com
Assessing pain in critically ill patients, particularly in nonverbal patients, is a great challenge. In this study, we validated a behavioral pain scale (BPS) in critically ill, sedated, and mechanically ventilated patients. The BPS score was the sum of 3 subscales that have a range score of 1-4: facial expression, upper limb movements, and compliance with mechanical ventilation. Two assessors observed and scored pain simultaneously with the BPS at rest and during painful procedures. The psychometric properties of the BPS that were studied were reliability, validity, and responsiveness. We achieved 360 observations in 30 patients. The BPS was internally reliable (Cronbach alpha = 0.72). The intraclass correlation coefficient to evaluate inter-rater reliability was high (0.95). Validity was demonstrated by the change in BPS scores, which were significantly higher during painful procedures, with averages of 3.9 +/- 1.1 at rest and 6.8 +/- 1.9 during procedures (P < 0.001), and by the principal components factor analysis, which revealed a large first-factor accounting for 65% of the variance in pain expression. The BPS exhibited excellent responsiveness, with an effect size ranging from 2.2 to 3.4. This study demonstrated that the BPS can be valid and reliable for measuring pain in noncommunicative intensive care unit patients.
PMID: 16244013 [PubMed - in process]
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Sacroiliac joint pain: a comprehensive review of anatomy, diagnosis, and treatment.
Cohen SP.
Johns Hopkins Hospital Pain Management Center 550 North Broadway, Suite 301 Baltimore, MD 21205, USA. scohen40@jhmi.edu
Sacroiliac (SI) joint pain is a challenging condition affecting 15% to 25% of patients with axial low back pain, for which there is no standard long-term treatment. Recent studies have demonstrated that historical and physical examination findings and radiological imaging are insufficient to diagnose SI joint pain. The most commonly used method to diagnose the SI joint as a pain generator is with small-volume local anesthetic blocks, although the validity of this practice remains unproven. In the present review I provide a comprehensive review of the anatomy, function, and mechanisms of injury of the SI joint, along with a systematic assessment of its diagnosis and treatment.
Publication Types:
PMID: 16244008 [PubMed - in process]
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Multimodal analgesia with gabapentin and local anesthetics prevents acute and chronic pain after breast surgery for cancer.
Fassoulaki A, Triga A, Melemeni A, Sarantopoulos C.
Department of Anesthesiology, Aretaieion Hospital, Medical School, University of Athens, Athens, Greece. afassou1@otenet.gr
We evaluated the effect of multimodal analgesia on acute and chronic pain after breast surgery for cancer. Fifty patients scheduled for breast cancer surgery were blindly randomized to receive gabapentin, eutectic mixture of local anesthetics cream, and ropivacaine in the wound or three placebos. Pain (visual analog scale) and analgesics were recorded in the postanesthesia care unit (PACU) 3, 6, and 9 h and 8 days after surgery. Three and 6 mo later, patients were assessed for chronic pain. The treatment group consumed less paracetamol in the PACU (469 versus 991 mg; P < 0.002) and less Lonalgal (1.0 versus 4.4 tablets; P = 0.003) than the controls, exhibited lower visual analog scale scores at rest in the PACU (P = 0.001) and on postoperative Days 1, 3, and 5 (P = 0.040, P = 0.015, and P = 0.045, respectively), and after movement in the PACU (P = 0.001) and on postoperative Days 2, 4, and 8 (P = 0.028, P = 0.007, and P = 0.032, respectively). Three and 6 mo after surgery, 18 of 22 (82%) and 12 of 21 (57%) of the controls reported chronic pain versus 10 of 22 (45%) and 6 of 20 (30%) in the treatment group (P = 0.028 and P = 0.424, respectively); 5 of 22 and 4 of 21 of the controls required analgesics versus 0 of 22 and 0 of 20 of those treated (P = 0.048 and P = 0.107, respectively). Multimodal analgesia reduced acute and chronic pain after breast surgery for cancer.
Publication Types:
PMID: 16244006 [PubMed - in process]
Prescribing methadone as an analgesic.
Dart RC, Woody GE, Kleber HD.
Publication Types:
PMID: 16230741 [PubMed - indexed for MEDLINE]
Psychosocial functioning of mothers with chronic pain: a comparison to pain-free controls.
Evans S, Shipton EA, Keenan TR.
Department of Psychology, University of Canterbury, Christchurch, New Zealand.
This study compared the functioning of mothers experiencing chronic pain and control mothers on a range of psychosocial variables. Participants included 39 mothers with chronic pain conditions ranging from migraine and arthritis to chronic neck and back pain and 35 control mothers with out chronic pain. Analyses indicated that mothers with chronic pain experienced more physical, psychological and social difficulties when compared to controls. More difficulties were reported in completing day-to-day parenting tasks in mothers with chronic pain. Consistent with the biopsychosocial model of chronic pain, psychosocial variables accounted for approximately half of the variance in chronic pain mothers' physical functioning scores. The importance of psychological variables in the experience of chronic pain, the potential reduction in parenting efficacy and the risk that these influences hold for children are discussed.
PMID: 16246821 [PubMed - in process]
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Effect of long-term neck muscle training on pressure pain threshold: a randomized controlled trial.
Ylinen J, Takala EP, Kautiainen H, Nykanen M, Hakkinen A, Pohjolainen T, Karppi SL, Airaksinen O.
Department of Physical and Rehabilitation Medicine, Jyvaskyla Central Hospital, Keskussairaalantie 19, 40620 Jyvaskyla, Finland. jari.ylinen@ksshp.fi
Muscle tenderness has been measured in several studies to evaluate effectiveness of treatment methods, but only short-term results have been reported so far. The aim of the present study was to evaluate the long-term effects of two different muscle training methods on the pressure pain threshold of neck muscles in women with neck pain. Altogether 180 woman with chronic, non-specific neck pain were randomized into three groups: neck muscle endurance training, neck muscle strength training and control groups. The main outcome measures included pressure pain threshold measurement at six muscle sites and on the sternum. Neck pain was assessed by a visual analogue scale (VAS). At the 12-month follow-up statistically significantly higher pressure pain threshold values were obtained in both training groups at all muscle sites compared to the baseline, while no significant change occurred in the controls. Significantly higher changes in pressure pain threshold were detected at all six sites in the strength training group and at four out of six sites in the endurance training group compared to the control group. This is the first study to show an increase in pressure pain thresholds as a result of long-term muscle training. A decrease in neck pain was associated with reduced pressure pain sensitivity in neck muscles, showing that the pressure pain threshold may be a useful outcome measure of the effectiveness of neck muscle rehabilitation.
PMID: 16246820 [PubMed - in process]
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Sexual dysfunction and chronic pain: the role of psychological variables and impact on quality of life.
Kwan KS, Roberts LJ, Swalm DM.
Department of Pain Management, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia. Kellie.Kwan@health.wa.gov.au
We report two studies examining the prevalence of sexual dysfunction, and the role of psychological variables, including quality of life, on sexual activity in patients at the commencement of an outpatient cognitive-behavioural pain management programme. In Study 1, 151 patients with non-cancer pain, predominantly of musculoskeletal origin, completed a range of standardised measures, including the Pain Disability Index, Beck Depression Inventory and Coping Strategies Questionnaire. Sexual dysfunction was common, and using stepwise multiple regression analysis was found to be more frequently reported by those with greater disability and depression, shorter pain duration, and infrequent use of coping self-statements. Study 2 was a pilot investigation of the impact of sexual dysfunction on quality of life (as measured by the WHOQOL-100) in a similar sample (n=41). Although sexual dysfunction was again commonly reported, subjects perceived it had less importance in quality of life than did other factors. The combined results support the previously proposed notion of adaptation to the impact of chronic illness on sexual function. In conclusion, sexual dysfunction is common in this population and is predicted by psychological factors and pain duration. However, other issues impact more significantly on quality of life. Therapeutic approaches to sexual dysfunction in these patients might best be focused on improving psychological factors, particularly depression and coping skills.
PMID: 16246817 [PubMed - in process]
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Pain-related fear at the start of a new low back pain episode.
Sieben JM, Portegijs PJ, Vlaeyen JW, Knottnerus JA.
Department of General Practice, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands. judith.sieben@hag.unimaas.nl
Previous research supports the fear-avoidance model in explaining chronic low back pain (LBP) disability. The aims of the present study were to determine: (1) whether fear-avoidance model variables are associated already during acute stages of LBP and (2) whether (increases in) pain-related fear are associated with other patient characteristics routinely assessed by the General Practitioner (GP). General practice patients consulting because of a new episode of LBP completed questionnaires on pain-related fear, avoidance, pain and disability. A sample of 247 acute LBP patients (median duration of current episode was 5 days) was collected. Significant associations were found between pain intensity, pain-related fear, avoidance behaviour and disability, but correlations were generally modest. A strong association was found between pain and disability. Pain-related fear was slightly higher in patients reporting low job satisfaction and in those taking bedrest. These results suggest that the fear-avoidance model as it was developed and tested in chronic LBP, might not entirely apply to acute LBP patients. Future research should focus on the transition from acute to chronic LBP and the shifts that take place between fear-avoidance model associations.
PMID: 16246816 [PubMed - in process]
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Paediatric cancer pain management using the WHO analgesic ladder - results of a prospective analysis from 2265 treatment days during a quality improvement study.
Zernikow B, Smale H, Michel E, Hasan C, Jorch N, Andler W.
Children's Pain Therapy and Pediatric Palliative Care, Children's Hospital Datteln, Witten/Herdecke University, Dr. Friedrich-Steiner Strasse 5, D-45711 Datteln, Germany.
OBJECTIVE: To collect data on pain management in paediatric oncology with respect to the WHO ladder approach. SETTING, DESIGN, PATIENTS AND METHODS: Eight German tertiary care paediatric oncology centres prospectively documented all their in-patient pain treatment courses from June 1999 to December 2000. Pain was scored using a 1-6 faces scale. RESULTS: Two hundred and twenty four patients (median age, 9 years; range 0.2-32.1) were enrolled. Three hundred and thirty three pain episodes comprising a total of 2265 treatment days were documented. Pain was mostly therapy associated. The most frequently administered non-opioid analgesics were dipyrone and paracetamol. On WHO step 2, tramadol was almost the only opioid used. During tramadol monotherapy average daily pain scores were lower than with a combination of tramadol and non-opioid analgesics. On WHO step 3, morphine was at least part of the analgesic regimen on most treatment days. Strong opioids were combined with a non-opioid analgesic on 41% of the treatment days. The mean intravenous morphine equivalence dose was 0.034mg/kg/h. During opioid and non-opioid combination therapy, adverse effects were more frequent, and average pain scored higher than on opioid monotherapy. CONCLUSIONS: WHO-guidelines were closely followed in Germany and seem to provide effective analgesia for children with cancer pain. In our patient group there is no evidence that a combination of an opioid with a non-opioid is more effective than opioid therapy alone in in-patient paediatric oncology pain treatment.
PMID: 16243549 [PubMed - as supplied by publisher]
Abnormal forebrain activity in functional bowel disorder patients with chronic pain.
Kwan CL, Diamant NE, Pope G, Mikula K, Mikulis DJ, Davis KD.
Institute of Medical Science, University of Toronto, Ontario, Canada.
BACKGROUND: Abnormal cortical pain responses in patients with fibromyalgia and conversion disorder raise the possibility of a neurobiologic basis underlying so-called "functional" chronic pain. OBJECTIVE: To use percept-related fMRI to test the hypothesis that patients with a painful functional bowel disorder do not process visceral input or sensations normally or effectively at the cortical level. METHODS: Eleven healthy subjects and nine patients with irritable bowel syndrome (IBS) underwent fMRI during rectal distensions that elicited either a moderate level of urge to defecate or pain. Subjects continuously rated their rectal stimulus-evoked urge or pain sensations during fMRI acquisition. fMRI data were interrogated for activity related to stimulus presence and to specific sensations. RESULTS: In IBS, abnormal responses associated with rectal-evoked sensations were identified in five brain regions. In primary sensory cortex, there were urge-related responses in the IBS but not control group. In the medial thalamus and hippocampus, there were pain-related responses in the IBS but not control group. However, pronounced urge- and pain-related activations were present in the right anterior insula and the right anterior cingulate cortex in the control group but not the IBS group. CONCLUSIONS: Percept-related fMRI revealed abnormal urge- and pain-related forebrain activity during rectal distension in patients with irritable bowel syndrome (IBS). As visceral stimulation evokes pain and triggers unconscious processes related to homeostasis and reflexes, abnormal brain responses in IBS may reflect the sensory symptoms of rectal pain and hypersensitivity, visceromotor dysfunction, and abnormal interoceptive processing.
PMID: 16247056 [PubMed - in process]
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